Fighting Cancer, One Slide at a Time

talk to us

Genebiosolution > IHC Primary Antibody > AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker)

AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker)

Clone C2 (Concentrate)

AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Datasheet Make Enquiry

Specifications

Species

Mouse

Immunogen

Alpha fetoprotein (AFP) purified from serum of a hepatoma patient.

Clone

Isotype

IgG1, kappa

Species Reactivity

Reacts with human and mouse. Does not react with cow, dog, and rat. Others not known.

Positive Control

Hep-G2 cells. Fetal liver or hepatocellular carcinoma.

Specificity

It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop). This monoclonal antibody is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin.

Cellular Localization

Cytoplasmic.

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G0558RP

At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.