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Genebiosolution > IHC Primary Antibody > AMACR / p504S (Prostate Cancer Marker)

AMACR / p504S (Prostate Cancer Marker)

Rabbit Polyclonal (Concentrate)

AMACR is an enzyme that is involved in bile acid biosynthesis and β-oxidation of branchedchain fatty acids. AMACR is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.

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Specifications

Species

Rabbit

Immunogen

A synthetic peptide from human AMACR protein

Clone

Rabbit Polyclonal

Isotype

IgG

Species Reactivity

Human. Others not known.

Positive Control

HEK cells or Prostate Adenocarcinoma.

Specificity

This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S.

Cellular Localization

Cytoplasmic

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G0354RP

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