The β-Catenin Rabbit Monoclonal Antibody [Clone GRM276] is engineered for high-affinity detection of β-Catenin, a key component of the Wnt signaling pathway and an essential protein in cell-cell adhesion and gene transcription regulation. This antibody offers robust and specific staining patterns in formalin-fixed, paraffin-embedded (FFPE) tissues and is validated for IHC, Western blotting, and immunofluorescence. Aberrant β-catenin localization—especially nuclear accumulation—is implicated in numerous malignancies, including colorectal carcinoma, hepatocellular carcinoma, and medulloblastoma, making GRM276 a valuable tool in both cancer diagnostics and research.
GRM276
GRM276 reacts to human Beta-Catenin (Catenin beta-1). This antibody may also react to mouse or rat Beta-Catenin, as predicted by immunogen homology.
A peptide corresponding to human Beta-Catenin.
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.