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β-Catenin Rabbit Monoclonal Antibody

The β-Catenin Rabbit Monoclonal Antibody [Clone GRM276] is engineered for high-affinity detection of β-Catenin, a key component of the Wnt signaling pathway and an essential protein in cell-cell adhesion and gene transcription regulation. This antibody offers robust and specific staining patterns in formalin-fixed, paraffin-embedded (FFPE) tissues and is validated for IHC, Western blotting, and immunofluorescence. Aberrant β-catenin localization—especially nuclear accumulation—is implicated in numerous malignancies, including colorectal carcinoma, hepatocellular carcinoma, and medulloblastoma, making GRM276 a valuable tool in both cancer diagnostics and research.

Specifications

Clone Name

GRM276

Specificity

GRM276 reacts to human Beta-Catenin (Catenin beta-1). This antibody may also react to mouse or rat Beta-Catenin, as predicted by immunogen homology.

Immunogen

A peptide corresponding to human Beta-Catenin.

Application

Immunohistochemistry (IHC) Western Blot (WB)

Species Reactivity

Human

Conjugate

None

Intended Use

Research Use Only

Storage and Stability:

Stable for 1 Year at -20.0°C from date of receipt.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G1157RP