The ATRX Antibody (Rabbit Monoclonal) is a highly specific and sensitive antibody developed to detect the ATRX protein, a crucial chromatin remodeling factor involved in gene regulation, DNA methylation, and maintenance of genomic stability. This antibody is extensively validated for use in immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissue sections, as well as in Western blotting and other immunoassays. ATRX plays a significant role in chromatin remodeling and is implicated in various genetic disorders and cancers, including gliomas, pancreatic neuroendocrine tumors, and alpha-thalassemia. The presence or loss of ATRX expression serves as an important diagnostic and prognostic biomarker, especially in neuro-oncology. This rabbit monoclonal antibody provides robust nuclear staining with high specificity and low background, enabling accurate assessment of ATRX protein expression in tissue samples. Optimized for compatibility with automated IHC staining platforms and a broad range of detection systems, the ATRX Antibody (Rabbit Monoclonal) is an essential reagent for pathologists and researchers focused on cancer diagnostics, epigenetics, and chromatin biology. Key Features: Clone: Rabbit Monoclonal Target: ATRX protein (Alpha Thalassemia/Mental Retardation Syndrome X-linked) Application: Immunohistochemistry (IHC), Western blotting, and other immunoassays Sample Type: Formalin-fixed, paraffin-embedded (FFPE) tissues Staining Pattern: Nuclear staining indicating ATRX protein expression Use Cases: Diagnostic and prognostic marker in gliomas, neuroendocrine tumors, and genetic disorder research
IgG
Polyclonal
Affinity purification Immunogen
Liquid
Recombinant Fragment Protein within Human ATRX aa 2200-2450. The exact immunogen used to generate this antibody is proprietary information.
0.27 - 1.31 mg/mL The concentration of this product may be batch-dependent
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
