The CD1a Rabbit Monoclonal Antibody (Clone RM393) is a high-affinity, rigorously validated antibody designed for the specific detection of CD1a, a transmembrane glycoprotein expressed predominantly on Langerhans cells, cortical thymocytes, and select dendritic cell subsets. CD1a plays a central role in presenting lipid antigens to T cells, making it a vital marker for research in immune function, dermatopathology, and hematologic malignancies. Clone RM393 is a next-generation rabbit monoclonal antibody offering enhanced sensitivity and specificity compared to conventional mouse antibodies. It provides crisp membranous staining with low background in formalin-fixed paraffin-embedded (FFPE) tissue sections, making it highly suitable for immunohistochemistry (IHC) applications. RM393 is especially effective for detecting Langerhans cells in normal and diseased skin, aiding in the diagnosis of conditions such as Langerhans Cell Histiocytosis (LCH), cutaneous T-cell lymphomas, and other immune-related skin disorders. This antibody is widely used in clinical and translational research, as well as routine pathology, offering reliable performance in multiplex immunostaining, tumor microenvironment profiling, and T-cell development studies. Its rabbit origin provides superior epitope recognition, making RM393 a preferred choice in studies requiring high signal clarity, especially in difficult or low-expression tissues.
GRM393
GRM393 reacts to human T-cell surface glycoprotein CD1a
A peptide corresponding to the N-terminus of human T-cell surface glycoprotein CD1a
Immunohistochemistry (IHC)
Human thymus tissue
Plasma membrane and early endocytic vesicles
Human
Research Use Only
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
