The Dimethyl-Histone H3 (Lys4) Rabbit Monoclonal Antibody (Clone GRM135) is specifically developed to recognize histone H3 dimethylated at lysine 4 (H3K4me2), a histone mark associated with transcriptional initiation and enhancer regions. GRM135 is validated for chromatin immunoprecipitation (ChIP), demonstrating high affinity and specificity with no cross-reactivity to mono- or tri-methylated forms. This antibody is ideal for epigenetic profiling and studies of chromatin remodeling, transcriptional regulation, and gene activation.
GRM135
GRM135 reacts to Histone H3 dimethylated at Lysine 4 (K4me2). No cross reactivity with monomethylated Lysine 4 (K4me1), trimethylated Lysine 4 (K4me3), or other methylations in histone H3.
A dimethyl-peptide corresponding to Dimethyl-Histone H3 (Lys4).
Chromatin IP (ChIP) Western Blot (WB) Immunocytochemistry (ICC) ELISA Multiplex Immunohistochemistry (IHC)
Human Vertebrates
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.