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Genebiosolution > IHC Primary Antibody > Anti-Histone H2AX

Anti-Histone H2AX Rabbit Monoclonal Antibody

The Anti-Histone H2AX Rabbit Monoclonal Antibody (Clone GRM214) specifically recognizes histone H2A.X, a variant of histone H2A that plays a critical role in the cellular response to DNA double-strand breaks (DSBs). Upon DNA damage, H2AX is rapidly phosphorylated at Ser139 to form γH2AX, a key marker for DNA damage signaling and repair. Clone GRM214 detects total H2A.X, enabling foundational studies in chromatin biology and genome integrity.

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Specifications

Clone Name

GRM214

Specificity

GRM214 reacts to Histone H2AX protein, independent of post-translational modifications. No cross reactivity with other histone proteins. .

Immunogen

A peptide corresponding to the C-terminus of human Histone H2AX

Application

Western Blot (WB) Immunocytochemistry (ICC) ELISA Multiplex

Species Reactivity

Human Vertebrates

Conjugate

None

Intended Use

Research Use Only

Storage and Stability:

Stable for 1 Year at -20.0°C from date of receipt.

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G1090RP

At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.