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Anti-Human Lambda Light Chain Antibody (Ig)

Here’s a detailed SEO-optimized product description for your Anti-Human Lambda Light Chain Antibody (Ig) under GeneBioSolution branding: Anti-Human Lambda Light Chain Antibody (Ig) – Product Description The Anti-Human Lambda Light Chain Antibody (Ig) from GeneBioSolution is a high-quality antibody validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues. Lambda light chains are one of the two types of immunoglobulin light chains produced by plasma cells and B lymphocytes, forming an essential component of antibodies. This antibody provides sensitive and specific cytoplasmic staining of lambda light chains, with minimal background. It is routinely used in diagnostic pathology to evaluate light chain restriction, an important diagnostic marker in plasma cell neoplasms (e.g., multiple myeloma, plasmacytoma) and certain B-cell lymphomas. When used alongside Anti-Kappa Light Chain Antibody, this antibody enables the determination of the kappa/lambda ratio, helping distinguish monoclonal (neoplastic) plasma cell proliferations from polyclonal (reactive) conditions. In addition to clinical diagnostics, the Anti-Lambda Light Chain Antibody is valuable in research applications, including studies of B-cell biology, immunoglobulin synthesis, autoimmune diseases, and hematologic malignancies. All GeneBioSolution antibodies undergo strict validation and quality control, ensuring lot-to-lot consistency, reproducibility, and compatibility with manual and automated IHC staining systems.

Specifications

Clone Name

GRM127

Specificity

GRM127 reacts to the lambda light chain of human immunoglobulins, and does not react to the kappa light chain. GRM127 does not react to monkey (Cyno or Rhesus) IgG, mouse IgG, rat IgG, or goat IgG.

Immunogen

Human IgG

Application

Immunohistochemistry (IHC) Flow Cytometry (FC) Immunocytochemistry (ICC) ELISA

Species Reactivity

Human.

Conjugate

None

Intended Use

Research Use Only

Storage and Stability

Stable for 1 Year at -20.0°C from date of receipt.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G1029RP