The Anti-Human IgA (α1 & α2) Antibodies from GeneBioSolution are high-quality reagents optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues. Immunoglobulin A (IgA) is the second most abundant immunoglobulin in human serum and the predominant antibody in mucosal secretions. It exists as two subclasses, IgA1 and IgA2, which differ in distribution and immune function. These antibodies provide sensitive and specific cytoplasmic staining of both IgA subclasses (α1 & α2), allowing comprehensive detection of IgA-producing plasma cells and mucosal immune responses. They are widely used in diagnostic pathology to evaluate plasma cell infiltrates, immunoglobulin subclass distribution, and immune-related disorders, including IgA nephropathy, autoimmune diseases, and chronic infections. In research, Anti-IgA (α1 & α2) antibodies support studies on mucosal immunity, gastrointestinal pathology, respiratory infections, and B-cell biology, offering insight into immune defense mechanisms and antibody subclass regulation. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, high specificity, and reproducible results on both manual and automated IHC staining systems. Clinical & Research Applications Detection of IgA1 and IgA2 plasma cells in tissue sections Diagnostic aid in IgA nephropathy, autoimmune diseases, and immune deficiency syndromes Research into mucosal immunity, gastrointestinal pathology, and chronic infections Analysis of IgA subclass distribution in plasma cell disorders and immune response studies
GRM128
GRM128 reacts to human IgA, including both IgA1 and IgA2. No cross reactivity with human IgG, IgM, IgD, or IgE.
Human IgA
ELISA Immunocytochemistry (ICC) Immunohistochemistry (IHC)
Human.
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
