The Anti-INI1 Rabbit Monoclonal Antibody [Clone GRM468] targets INI1, a tumor suppressor and essential component of the SWI/SNF chromatin remodeling complex involved in regulating gene expression by modifying chromatin structure. INI1 loss or mutation is implicated in aggressive cancers such as malignant rhabdoid tumors and other sarcomas. This antibody is a reliable tool for detecting INI1 expression and studying its role in chromatin remodeling, tumor suppression, and cancer biology.
GRM468
GRM468 reacts to human INI1 (SNF5/SMARCB1). This antibody may also react to mouse or rat INI1, as predicted by immunogen homology.
A peptide corresponding to the C-terminus of human INI1 (SNF5/SMARCB1)
Immunochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.