MSH6 Rabbit Monoclonal Antibody is a highly specific antibody developed to detect MutS homolog 6 (MSH6), a critical component of the DNA mismatch repair (MMR) system. MSH6 forms a heterodimer with MSH2 to recognize base-base mismatches and small insertion-deletion loops during DNA replication. Loss or mutation of MSH6 is associated with Lynch syndrome and various sporadic cancers. This rabbit monoclonal antibody provides excellent sensitivity and specificity for applications such as immunohistochemistry and Western blotting, making it a valuable tool in cancer diagnostics and research related to genomic stability and DNA repair pathways.
GRM376
GRM376 reacts to human DNA mismatch repair protein MSH6
Mammalian cell expressed recombinant protein fragment of human MSH6
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
