he Myeloperoxidase (MPO) Antibody (Rabbit Monoclonal) from GeneBioSolution is a high-quality antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). MPO is a lysosomal enzyme expressed in the primary granules of myeloid precursor cells and mature neutrophils, playing a critical role in microbial defense and oxidative metabolism. This antibody provides sensitive and specific cytoplasmic staining of MPO in myeloid cells, with minimal background. MPO is a key diagnostic marker in hematopathology, widely used to identify acute myeloid leukemia (AML), myeloid sarcoma, and other myeloid lineage disorders. It is also valuable in distinguishing myeloid neoplasms from lymphoid malignancies. In addition to diagnostics, MPO is applied in inflammation and immunology research, particularly in studies of neutrophil biology, oxidative stress, and host–pathogen interactions. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, high specificity, and reproducible IHC results across manual and automated staining systems. Clinical & Research Applications Diagnostic marker for acute myeloid leukemia (AML) and myeloid sarcoma Differentiation of myeloid vs lymphoid leukemias Research on neutrophil activity, inflammation, and oxidative stress Studies into immune defense and host–pathogen interactions
GRM407
GRM407 reacts to human MPO. This antibody may also react to mouse or rat MPO, as predicted by immunogen homology.
A peptide corresponding to the internal region of light chain on human MPO
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
