p63 antibody (Rabbit Monoclonal)

p63 (Tumor Protein 63) Rabbit Monoclonal Antibody

The P63 antibody (Rabbit Monoclonal) is a highly sensitive and specific nuclear marker widely used in immunohistochemistry (IHC) for cancer diagnostics and research. P63, a transcription factor from the p53 gene family, is strongly expressed in basal cells of stratified epithelia and in myoepithelial cells, making it an essential tool for evaluating epithelial differentiation. This antibody provides crisp, reliable nuclear staining and demonstrates superior performance compared to traditional mouse clones, offering enhanced sensitivity and lower background in formalin-fixed paraffin-embedded (FFPE) tissues. Clinically, the P63 rabbit monoclonal antibody plays a key role in distinguishing squamous cell carcinoma from adenocarcinoma, identifying urothelial carcinomas, and confirming the presence or absence of myoepithelial cells in breast pathology, which is critical for differentiating invasive carcinoma from in situ lesions. In prostate pathology, the absence of P63 expression assists in confirming a diagnosis of prostate adenocarcinoma. Its consistent and reproducible staining makes it suitable for both routine diagnostics and advanced research applications. Validated for use with heat-induced epitope retrieval (HIER), this antibody is optimized for automated and manual IHC staining systems, ensuring flexibility in laboratory workflows. Available in both concentrated and ready-to-use formats, the P63 rabbit monoclonal antibody is QC tested for batch-to-batch reliability and supplied in multiple vial sizes to meet diverse clinical and research needs.