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p70S6K Rabbit Monoclonal Antibody

The p70S6K antibody (Rabbit Monoclonal) is a highly specific and sensitive reagent designed for the detection of p70 S6 Kinase, a key serine/threonine kinase in the mTOR signaling pathway. p70S6K plays a central role in regulating protein synthesis, cell growth, proliferation, and survival, making it an essential biomarker for cancer research, molecular biology, and translational studies. This rabbit monoclonal antibody delivers crisp, reproducible results in immunohistochemistry (IHC), western blotting (WB), and other immunoassays, with superior affinity and reduced background compared to conventional mouse monoclonals. In oncology research, p70S6K overexpression and activation have been associated with multiple malignancies, including breast, prostate, lung, and colorectal cancers, as well as resistance to targeted therapies. The p70S6K antibody provides reliable nuclear and cytoplasmic staining in FFPE tissue samples, enabling researchers to investigate tumor progression, therapeutic response, and signaling alterations in clinical and experimental models. Beyond cancer biology, it is also valuable for studying pathways linked to metabolism, diabetes, neurodegeneration, and aging.

Specifications

Clone Name

GRM438

Specificity

GRM438 reacts to human p70S6K.

Immunogen

A peptide corresponding to the N-terminus of p70S6K

Application

IHC, WB

Species Reactivity

Human

Conjugate

None

Intended Use

Research Use Only

Storage and Stability:

Stable for 1 Year at -20.0°C from date of receipt.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G1329RP