Anti-phospho-Akt (Ser473) Rabbit Monoclonal Antibody

The Anti-phospho-Akt (Ser473) Rabbit Monoclonal Antibody [Clone GRM251] is a highly specific and sensitive antibody designed to detect Akt only when phosphorylated at serine 473. Phosphorylation at Ser473 is essential for full activation of Akt, a key serine/threonine kinase involved in cell survival, proliferation, glucose metabolism, and angiogenesis. This antibody is an essential tool for studying PI3K/Akt pathway activation in cancer, metabolism, and signal transduction research.

Specifications

Clone Name

GRM251

Specificity

GRM251 reacts to Akt only when phosphorylated at Ser473. There is no cross-reactivity with Akt without phosphorylation at Ser473. This antibody may also react to bovine, mouse or rat Phospho-Akt (Ser473), as predicted by immunogen homology.

Immunogen

A phospho-peptide corresponding to human Phospho-Akt (Ser473)

Application

Immunohistochemistry (IHC) Western Blot (WB)

Species Reactivity

Human (Mouse, Rat, Bovine)

Conjugate

None

Intended Use

Research Use Only

Storage and Stability:

Stable for 1 Year at -20.0°C from date of receipt.