The Phospho-Stat3 (Tyr705) Rabbit Monoclonal Antibody [Clone GRM261] is a high-specificity antibody developed to detect Stat3 phosphorylated at tyrosine 705 (p-Stat3 Tyr705), a critical activation site for Stat3 signaling. This phosphorylation event is essential for Stat3 dimerization, nuclear translocation, and transcriptional activation in response to cytokines and growth factors. GRM261 is validated for multiple applications, including Western blotting, immunohistochemistry, and immunofluorescence, and is ideal for investigating pathways related to inflammation, cancer, and cellular stress response.
GRM261
GRM261 reacts to human Stat3 only when phosphorylated at Tyr705. There is no cross-reactivity to stat3 without phosphorylation at Tyr705. This antibody may also react to mouse or rat Phospho-Stat3 (Tyr705), as predicted by immunogen homology.
A phospho-peptide corresponding to human Phospho- Stat3 (Tyr705)
Immunohistochemistry (IHC) Western Blot (WB)
Human (Mouse, Rat)
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
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