The Anti-PTEN Rabbit Monoclonal Antibody (Clone GRM511) is a highly specific antibody designed to detect the PTEN (Phosphatase and Tensin Homolog) tumor suppressor protein. PTEN is a critical regulator of the PI3K/AKT signaling pathway, modulating cell proliferation, survival, and metabolism. Loss or mutation of PTEN is frequently associated with various cancers, including breast, prostate, and glioblastoma, making this antibody a vital tool for cancer research, diagnostics, and molecular pathology.
GRM511
This antibody reacts to human PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN)
A peptide corresponding to residues at the C-terminus of human PTEN
Immunohistochemistry (IHC) (optimized for the detection of endometrial carcinomas.)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.