The Rabbit IgG Fab Goat Monoclonal Antibody is a highly specific secondary reagent generated against the Fab fragment (antigen-binding domain) of rabbit IgG. By selectively binding to the Fab region, this antibody ensures accurate detection of rabbit primary antibodies while avoiding cross-reactivity with Fc-mediated interactions that can cause background noise. This makes it particularly valuable for applications where high signal-to-noise ratio and minimal non-specific binding are essential. As a goat-derived monoclonal antibody, it offers consistent epitope recognition, high affinity, and lot-to-lot reproducibility, surpassing polyclonal alternatives in assay precision. It is validated for use in ELISA, western blotting (WB), immunofluorescence (IF), and immunohistochemistry (IHC), delivering robust performance in both qualitative and quantitative immunodetection workflows. Biologically, Fab-specific secondary antibodies are indispensable for probing the antigen-binding activity of rabbit immunoglobulins while preventing interference from Fc interactions with complement proteins or Fc receptors on immune cells. This is particularly relevant in cell-based assays, tissue immunolabeling, and diagnostic histopathology, where Fc-mediated background can compromise specificity.
GRMG01
GRMG01 reacts to the Fab region of Rabbit IgG. No cross reactivity with human IgG, rat IgG, or mouse IgG.
Rabbit IgG
ELISA Western Blot (WB) (nonreduced)
Rabbit
None.
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
