The Smad4 Rabbit Monoclonal Antibody (Clone: GRM277) is a high-performance antibody specifically designed to detect Smad4, a central mediator in the TGF-β (Transforming Growth Factor-beta) signaling pathway. Smad4 plays a pivotal role in transducing extracellular signals from TGF-β family ligands to the nucleus, regulating gene expression involved in cell growth, apoptosis, and differentiation. Clone GRM277 offers superior sensitivity and specificity in immunohistochemistry, western blotting, and immunofluorescence applications.
GRM277
GRM277 reacts to human Smad4. This antibody may also react to mouse or rat Smad4, as predicted by immunogen homology.
A peptide corresponding to the C-terminus of human Smad4.
Immunohistochemistry (IHC) Western Blot (WB
Human (Mouse)
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.