The Spastin Rabbit Monoclonal Antibody is a highly specific antibody developed to detect spastin, a microtubule-severing protein involved in cytoskeletal dynamics and intracellular trafficking. Mutations in the spastin gene (SPAST) are a common cause of hereditary spastic paraplegia (HSP), a neurodegenerative disorder characterized by progressive weakness and stiffness of the lower limbs. This rabbit monoclonal antibody offers excellent sensitivity and specificity, making it ideal for applications such as Western blotting, immunohistochemistry, and immunofluorescence. It is widely used in neuroscience and cell biology research to study axonal transport, neurodegeneration, and cytoskeletal regulation.
GRM346
GRM346 reacts to human Spastin.
A peptide corresponding to the N-terminus of human Spastin.
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.