The Symmetric Dimethyl-Histone H4 (Arg3) Rabbit Monoclonal Antibody (Clone GRM459) is a highly specific antibody developed to recognize histone H4 when symmetrically dimethylated at arginine 3 (H4R3me2s). This post-translational modification plays a key role in epigenetic regulation, gene silencing, and chromatin remodeling. GRM459 delivers high sensitivity and specificity for detecting this histone mark in a variety of applications including chromatin immunoprecipitation (ChIP), western blotting, and immunostaining.
GRM459
GRM459 reacts to Histone H4 symmetric dimethylated at Arginine 3 (R3me2s). No cross reactivity with unmodified Arginine 3, monomethylated or asymmetric dimethylated Arginine 3, or other methylated Arginine in Histone H4.
A symmetric dimethyl-peptide corresponding to the symmetric demethylated Histone H4 (Arg3).
Western Blot Luminex
Human Vertebrates
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.