The TOP2A Rabbit Monoclonal Antibody [Clone GRM394] is designed for the sensitive and specific detection of Topoisomerase II Alpha (TOP2A)—a critical enzyme involved in DNA replication, transcription, chromosome condensation, and segregation. TOP2A is tightly regulated throughout the cell cycle and is highly expressed in proliferating cells, making it a reliable marker of cellular proliferation and a potential therapeutic target in oncology. Clone GRM394 provides excellent performance in formalin-fixed, paraffin-embedded (FFPE) tissue sections and is ideal for cancer research, particularly in assessing tumor aggressiveness and response to TOP2A-targeting chemotherapies such as anthracyclines.
GRM394
GRM394 reacts to TOP2A
A peptide corresponding to the C-terminus of human TOP2A
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
