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Genebiosolution > IHC Primary Antibody > Anti-Trimethyl-Histone H3 (Lys27)

Anti-Trimethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody

H3K27me3 is a hallmark of gene silencing and is catalyzed by the Polycomb Repressive Complex 2 (PRC2). It plays a central role in regulating gene expression during embryogenesis, X-chromosome inactivation, and cellular differentiation. Aberrant patterns of H3K27me3 are linked to tumorigenesis, stem cell dysregulation, and epigenetic plasticity in cancer. GRM175 provides researchers with a precise tool to study this key histone mark in normal and diseased states.

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Specifications

Clone Name

GRM175

Specificity

GRM175 reacts to Histone H3 trimethylated at Lysine 27 (K27me3). No cross reactivity non-modified Lysine 27, monomethylated Lysine 27 (K27me1) or dimethylated Lysine 27 (K27me2), or other methylations in histone H3.

Immunogen

A trimethyl-peptide corresponding to trimethyl-Histone H3 (Lys27).

Application

Chromatin IP (ChIP) Western Blot (WB) Immunohistochemistry (IHC) ELISA Multiplex

Species Reactivity

Human Vertebrates

Conjugate

None

Intended Use

Research Use Only

Storage and Stability:

Stable for 1 Year at -20.0°C from date of receipt.

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G1062RP

At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.