The Trimethyl-Histone H3 (Lys4) Rabbit Monoclonal Antibody (Clone GRM137) is specifically designed to recognize the trimethylated form of lysine 4 on histone H3 (H3K4me3). This histone modification is a key epigenetic mark associated with transcriptionally active promoters and is widely used as a chromatin signature for gene activation. GRM137 is highly specific, showing no cross-reactivity to unmodified, mono-, or dimethylated K4. It is validated for multiple applications including ChIP, WB, IHC, and IF.
GRM137
GRM137 reacts to Histone H3 trimethylated at Lysine 4 (K4me3). No cross reactivity with monomethylated Lysine 4 (K4me1), dimethylated Lysine 4 (K4me3), or other methylations in histone H3.
A trimethyl-peptide corresponding to Trimethyl-Histone H3 (Lys4).
Western Blot ELISA Multiplex Immunohistochemistry
Human Vertebrates
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
