Anti-Trimethyl-Phospho-Histone H3 (Lys9/Ser10) Rabbit Monoclonal Antibody

The Anti-Trimethyl-Phospho-Histone H3 (Lys9/Ser10) Rabbit Monoclonal Antibody [Clone GRM162] is a highly specific tool designed to recognize the unique combinatorial epigenetic mark H3K9me3S10ph — where lysine 9 is trimethylated and serine 10 is phosphorylated on histone H3. This dual modification is often associated with transcriptional activation of genes embedded in heterochromatic regions, especially under conditions such as cellular stress or during mitotic entry.

Specifications

Clone Name

GRM162

Specificity

GRM162 reacts to Histone H3 only when modified by both trimethylation at lysine 9 and phosphorylation at serine 10 (K9me3/S10p).

Immunogen

A trimethyl-phospho-peptide corresponding to Trimethyl- Phospho-Histone H3 (Lys9/Ser10).

Application

Western Blot (WB) ELISA Multiplex Immunohistochemistry (IHC)

Species Reactivity

Human Vertebrates

Conjugate

None

Intended Use

Research Use Only

Storage and Stability:

Stable for 1 Year at -20.0°C from date of receipt.