The TRK (pan) Rabbit Monoclonal Antibody [Clone GRM423] is designed for the detection of pan-TRK proteins, including TRKA (NTRK1), TRKB (NTRK2), and TRKC (NTRK3). These neurotrophic tyrosine receptor kinases play key roles in neuronal development and are known to form oncogenic fusions in a variety of adult and pediatric tumors. Clone GRM423 provides sensitive and specific detection of TRK family proteins in formalin-fixed, paraffin-embedded (FFPE) tissues, making it a valuable tool in both research and clinical pathology settings, particularly in identifying tumors with NTRK gene fusions.
GRM423
GRM423 reacts to human TRK. This antibody may also react to mouse or rat TRK, as predicted by immunogen homology.
A peptide corresponding to the C-terminus of human TRK
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
