The Phospho-EGFR (Tyr1068) Rabbit Monoclonal Antibody from GeneBioSolution is a highly specific antibody designed for immunohistochemistry (IHC) applications on formalin-fixed, paraffin-embedded (FFPE) tissues. Epidermal Growth Factor Receptor (EGFR) is a receptor tyrosine kinase critical to cell growth, survival, and differentiation. Phosphorylation at tyrosine 1068 (Tyr1068) is one of the key activation sites of EGFR, triggering downstream oncogenic signaling cascades including the PI3K/AKT and RAS/RAF/MEK/ERK pathways. This antibody provides sensitive and specific detection of EGFR phosphorylation at Tyr1068, enabling pathologists and researchers to assess tumor signaling activity, aggressiveness, and therapeutic response. Clinical & Research Applications Assessment of EGFR activation status in tumor biopsies Detection of phospho-EGFR (Tyr1068) expression in FFPE tissues by IHC Evaluation of cancers such as non-small cell lung carcinoma (NSCLC), colorectal cancer, breast carcinoma, and glioblastomas Research on drug resistance and EGFR-targeted therapies (TKIs, monoclonal antibodies) Oncology and translational research focused on cell proliferation, invasion, and EMT Key Features Clone: Rabbit Monoclonal (Phospho-specific to Tyr1068) Application: IHC on FFPE tissues Target Protein: Phospho-EGFR (Tyr1068) Diagnostic/Research Utility: NSCLC, colorectal carcinoma, breast cancer, glioblastoma Performance: High specificity for phosphorylated EGFR; strong, reproducible staining with low background Why GeneBioSolution? Strict validation across tumor tissue panels Optimized for manual and automated IHC platforms Guaranteed lot-to-lot consistency for reliable performance Designed to support both research laboratories and clinical studies
GRM515
This antibody reacts to human VEGFR2 (KDR) (FLK-1) (CD309)
A peptide corresponding to residues near the C-terminus of human VEGFR2
Immunohistochemistry (IHC); Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
