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Genebiosolution > IHC Primary Antibody > BOB1 Antibody (mouse monoclonal)

BOB1 Antibody ( mouse monoclonal )

GM74/Monospecific Mouse/Monoclonal

Gene Bio Solution BOB1 Antibody. Gene bio solution’s mouse monoclonal antibody recognizes BOB1, where expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB1. Conversely, only some cases of classical Hodgkin lymphoma show BOB1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.

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Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Tonsil

Visualization

Cytoplasmic and nuclear

Isotype

IgG2b /κ

Immunogen

Recombinant human BOB1 (POU2AF1) protein fragment (around aa 148-255)

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G2384RP

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