Fighting Cancer, One Slide at a Time

BRCA-1 Antibody

GR455/Rabbit/Monoclonal

Gene Bio Solution BRCA-1 Antibody. Gene bio solution’s high quality rabbit recombinant monoclonal antibody recognizes the BRCA-1 protein in immunohistochemistry (IHC) applications. The BRCA-1 gene codes for a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor. Mutations in the BRCA-1 genes have been linked to an increased risk of developing breast and ovarian cancers. Individuals with certain mutations in BRCA-1 may have a higher likelihood of developing these cancers compared to those without the mutations. BRCA-1 immunohistochemistry is commonly used in research and clinical settings to provide valuable information about the status of the BRCA-1 protein in cancerous and non-cancerous tissues. Changes in BRCA-1 protein can be associated with certain types of breast and ovarian cancers, and this information may be used in the diagnosis, prognosis, and treatment planning for patients.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Breast carcinoma with BRCA-1 gene mutation

Visualization

Nuclear

Isotype

IgG

Immunogen

Synthetic peptide to human BRCA1 protein

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2812RP