C3c

C3c\FITC

Complement component 3 (C3) is a critical protein in the immune system, forming a key part of the complement cascade and innate immunity.
• C3 glomerulopathy describes kidney conditions where C3 deposits accumulate in the glomeruli without significant immunoglobulin presence, hinting at alternative complement pathway activation.
• Variants include Dense Deposit Disease (DDD) and C3 Glomerulonephritis (C3GN), sometimes linked to hereditary defects like CFHR5 nephropathy.
• Lupus nephritis involves kidney inflammation due to Systemic Lupus Erythematosus (SLE) and typically shows immunofluorescent positivity for IgG, IgA, IgM, C3, and C1q.

INTENDED USE

This antibody is intended for Research Use Only and is not for diagnostic or therapeutic procedures.