CA125 (OCA125/1900) is a monoclonal antibody that targets the cancer antigen 125, a high-molecular-weight glycoprotein commonly used as a tumor marker, especially in ovarian cancer. This antigen is expressed on the surface of epithelial cells derived from coelomic and Müllerian epithelia, including the lining of the fallopian tubes, endometrium, and peritoneum. The CA125 (OCA125/1900) antibody is frequently employed in immunohistochemistry to detect the presence of CA125 in tissue samples, aiding in the diagnosis and monitoring of ovarian carcinomas as well as other gynecological malignancies. It can also help differentiate between ovarian tumors and other malignancies, as elevated CA125 expression is often correlated with tumor burden and disease progression. Overall, CA125 (OCA125/1900) is a vital tool in both clinical and research settings for the evaluation of epithelial ovarian cancers and related conditions.
Mouse
Full length native MUC16 protein purified from human ovarian carcinoma
OCA125/1900
IgG1/Kappa
This antibody has been pre-titered and quality controlled to work on formalin-fixed paraffin- embedded as well as acetone fixed cryostat tissue sections.
Human
MDA-MB-468 cells. Ovarian Cancer
Cell membrane, Extracellular space, Secreted