The Cadherin-17 Antibody (Clone SP183) is a rabbit monoclonal antibody specifically designed for the detection of Cadherin-17, also known as liver–intestine cadherin. Cadherin-17 is a transmembrane protein involved in cell adhesion and is highly expressed in gastrointestinal epithelium. This antibody is validated for use in immunohistochemistry (IHC), particularly on formalin-fixed, paraffin-embedded (FFPE) tissues. Clone SP183 offers high specificity and sensitivity, making it an excellent marker for gastrointestinal adenocarcinomas, including colorectal and gastric cancers. It is a valuable tool in differential diagnosis, especially for distinguishing primary gastrointestinal tumors from metastatic carcinomas.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Normal colon/colon adenocarcinoma
Cytoplasmic and membranous
IgG
Recombinant fragment (around aa 242-418) of human cadherin 17 protein (CDH17)
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
