The Calcitonin Antibody is a high-affinity antibody designed for the specific detection of calcitonin, a peptide hormone produced primarily by the parafollicular cells (C cells) of the thyroid gland. Calcitonin plays a crucial role in calcium and phosphate metabolism by regulating bone resorption and maintaining calcium homeostasis. This antibody is widely used in immunohistochemistry (IHC), immunofluorescence (IF), western blotting (WB), and ELISA applications to detect and quantify calcitonin expression in biological samples. It is especially valuable in the diagnosis and research of medullary thyroid carcinoma (MTC), where calcitonin serves as a specific tumor marker. The Calcitonin Antibody offers strong, specific staining of calcitonin-producing cells in formalin-fixed, paraffin-embedded (FFPE) tissues and fresh or frozen samples. It is validated for use in both manual and automated staining platforms, ensuring consistent and reliable results across various laboratory workflows.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Thyroid or medullary carcinoma
Cytoplasmic
IgG2b /κ
Recombinant fragment of human Calcitonin protein (around aa 3-116)
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
