The CD11c antibody [5D11] (Mouse Monoclonal) is a highly specific and reliable antibody developed for the sensitive detection of CD11c, an integrin alpha X chain prominently expressed on dendritic cells, monocytes, macrophages, and select activated lymphocyte populations. As a critical component of the immune system, CD11c plays an essential role in cell adhesion, migration, and antigen presentation, making it a key biomarker for researchers investigating immune responses, inflammation, and tumour microenvironments. This mouse monoclonal antibody exhibits excellent specificity and affinity, ensuring consistent and reproducible detection of CD11c-positive cells in a wide range of biological samples. Extensively validated for multiple research applications, including flow cytometry, immunohistochemistry (IHC), immunofluorescence (IF), and Western blot, this antibody enables precise characterization and quantification of dendritic cells and myeloid populations in human and animal tissues. It is widely utilized in immunology, cancer biology, and cell signaling studies, helping scientists to explore immune cell dynamics, inflammatory pathways, and disease mechanisms at the cellular level. The antibody’s strong performance on formalin-fixed paraffin-embedded (FFPE) tissues makes it particularly valuable for histological analyses in clinical and translational research. Designed for researchers demanding high sensitivity and minimal background staining, this CD11c mouse monoclonal antibody provides clear and distinct labeling of CD11c-expressing cells, facilitating detailed immune profiling and functional assays. Whether studying autoimmune diseases, cancer immunology, or infectious diseases, this antibody supports robust and reproducible results critical for advancing biomedical research. Key features of this antibody include its mouse monoclonal origin, high specificity to CD11c, and broad application versatility, making it an indispensable reagent for laboratories focused on immune cell biology and pathophysiology
Mouse
Monoclonal
5D11
IgG2a
IHC-P
Human
Store at 4ºC. do not freeze.
Prokaryotic recombinant protein corresponding to 258 amino acids from the N-terminus of the external domain of the CD11cmolecule.
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