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CD138

The CD138 Antibody (Rabbit Monoclonal) Clone ( EP 201 ) is a high-affinity, highly specific antibody developed for the detection of CD138, also known as syndecan-1—a transmembrane heparan sulfate proteoglycan expressed on plasma cells, epithelial cells, and various tumor types. CD138 plays a critical role in cell adhesion, proliferation, and maintaining epithelial integrity. It is widely recognized as a key biomarker for identifying plasma cells in multiple myeloma and other B-cell lymphoproliferative disorders, as well as for evaluating epithelial differentiation in cancer research. This rabbit monoclonal antibody delivers superior sensitivity and specificity compared to conventional mouse antibodies, making it ideal for applications such as immunohistochemistry (IHC). Its robust performance on formalin-fixed paraffin-embedded (FFPE) tissues enables researchers and pathologists to clearly visualize CD138 expression in both normal and pathological samples. The antibody is also frequently used to assess tumor progression, plasma cell infiltration, and epithelial cell dynamics in research focused on oncology, immunology, and regenerative medicine. The CD138 Rabbit Monoclonal Antibody is particularly valuable in the diagnosis and monitoring of multiple myeloma, plasma cell neoplasms, and epithelial-derived tumors, offering clean, reproducible staining and minimal background signal. Its rabbit origin enhances antigen recognition, making it an excellent choice for detecting low-abundance targets or subtle expression differences in tissue samples.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Tonsil

Visualization

Cell membrane/cytoplasmic

Isotype

IgG

Immunogen

Recombinant fragment (around aa1-250) of human CD138 protein (exact sequence is proprietary)

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2490RP