CD140b (PDGF Receptor beta) Antibody

CD140b (PDGF Receptor beta) Antibody

The CD140b (PDGF Receptor Beta) Antibody is a high-affinity, highly specific antibody designed for the detection of platelet-derived growth factor receptor beta (PDGFRβ), also known as CD140b. PDGFRβ is a transmembrane tyrosine kinase receptor predominantly expressed on pericytes, vascular smooth muscle cells, and mesenchymal stem cells, where it plays a key role in angiogenesis, cell proliferation, migration, and tissue remodeling. This antibody is widely used as a marker for mesenchymal lineage cells and for investigating tumor stroma, fibrosis, and vascular biology in both normal and pathological conditions. Validated for multiple applications including immunohistochemistry (IHC) and cancer research this CD140b antibody ensures strong, specific binding with minimal background, making it suitable for both fresh and formalin-fixed paraffin-embedded (FFPE) tissues. Its high performance across various sample types allows for detailed analysis of PDGFRβ expression in a range of research areas such as cancer biology, developmental studies, wound healing, and stem cell research. Researchers rely on this antibody to study tumor microenvironments, characterize perivascular cells, monitor fibroblast activation, and evaluate PDGF signaling pathways in disease progression and therapeutic development. With high sensitivity and robust reproducibility, the CD140b antibody is an essential tool for dissecting cellular interactions and signaling mechanisms in complex tissue environments.