The CD15 Antibody (Rabbit Monoclonal) is a high-affinity, highly specific antibody developed for the sensitive detection of CD15, also known as the Lewis X antigen, a carbohydrate epitope predominantly expressed on the surface of granulocytes such as neutrophils and eosinophils. This rabbit monoclonal antibody combines the advantages of rabbit-derived antibodies—such as superior affinity and specificity—with the versatility required for a range of immunodetection techniques, making it an excellent choice for both research and diagnostic applications. CD15 is widely recognized as a crucial marker in hematology and oncology, especially for identifying Reed-Sternberg cells in Hodgkin lymphoma, as well as other hematologic malignancies. The CD15 Rabbit Monoclonal Antibody provides crisp, reproducible staining in immunohistochemistry (IHC) on formalin-fixed paraffin-embedded (FFPE) tissue sections, enabling precise visualization of CD15-positive cells in clinical and research samples. The enhanced sensitivity and specificity of this rabbit monoclonal antibody make it ideal for detecting low-abundance CD15 expression and minimizing background staining, facilitating accurate analysis of granulocyte distribution, immune responses, and tumor microenvironment dynamics. It supports studies focused on inflammation, immune cell trafficking, hematopoietic lineage differentiation, and cancer progression. In summary, the CD15 Antibody (Rabbit Monoclonal) is a powerful, versatile reagent for accurate detection and detailed study of granulocytes and CD15-positive tumor cells. Its superior affinity and performance across multiple platforms make it a valuable tool for both clinical diagnostics and advanced immunological research.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Hodgkin lymphoma
Cell membrane and granular perinuclear
IgG
Purified human neutrophils (FUT4/815); Myelomonocytic leukemia cells (BRA-4F1)