The CD2 Antibody (Rabbit Monoclonal, Clone EP222) is a high-affinity, highly specific antibody developed for the reliable detection of CD2, a surface glycoprotein expressed on mature T lymphocytes, natural killer (NK) cells, and a subset of thymocytes. CD2 plays a critical role in T-cell activation, adhesion, and immune synapse formation, making it a valuable marker in immunophenotyping, T-cell biology, and hematologic malignancy diagnostics. Clone EP222 is a rabbit monoclonal antibody engineered for enhanced epitope recognition and signal clarity. It delivers crisp membranous staining with minimal background in formalin-fixed paraffin-embedded (FFPE) tissues, making it ideal for immunohistochemistry (IHC). This antibody is extensively utilized in diagnostic pathology for identifying T-cell neoplasms, such as T-cell lymphomas, and for distinguishing T-cell populations in lymphoid tissues. It is also valuable in immuno-oncology, autoimmune disease research, and tumor microenvironment profiling, especially when integrated into multiplex panels. In summary, the CD2 Rabbit Monoclonal Antibody (Clone EP222) is a sensitive and specific reagent for the detection of T cells and NK cells in tissue sections and cell suspensions. Its advanced rabbit monoclonal format ensures robust performance across multiple platforms, making it a trusted tool for researchers and clinicians working in immunology, hematology, and cancer immunotherapy.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Tonsil
Membranous, cell surface
IgG
Recombinant fragment of human CD2 protein