CD21 Antibody (Rabbit Monoclonal)

CD21 Antibody (Rabbit Monoclonal)

The CD21 antibody (rabbit monoclonal) clone EP3093 is a highly specific and sensitive antibody designed for the detection of human CD21 (complement receptor 2, CR2), a cell surface receptor expressed on mature B lymphocytes and follicular dendritic cells. This antibody is widely used in immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues, as well as in flow cytometry and immunofluorescence applications. Clone EP3093 provides robust and reproducible membrane staining with minimal background, making it an excellent tool for research and clinical diagnostics. CD21 plays a key role in the immune response by binding complement fragments and facilitating antigen presentation, making it a critical biomarker for identifying mature B cells and follicular dendritic cells within lymphoid tissues. This antibody is valuable for studies involving lymphoid tissue characterization, autoimmune diseases, and hematological malignancies such as B-cell lymphomas. The rabbit monoclonal format offers enhanced affinity and specificity compared to traditional mouse antibodies, ensuring consistent and reliable results across various assay platforms. Recommended positive controls include human tonsil, lymph node, and spleen tissues, enabling accurate validation of staining. The CD21 antibody clone EP3093 is an essential reagent for advancing immunological research and diagnostic pathology involving B cell and follicular dendritic cell populations.