The CD25 Antibody (Rabbit Monoclonal, Clone RM418) is a highly specific and sensitive antibody designed for the detection of CD25, the interleukin-2 receptor alpha chain (IL-2Rα), expressed predominantly on activated T cells, regulatory T cells (Tregs), and certain hematological malignancies. CD25 plays a crucial role in immune response regulation, T-cell activation, and autoimmune disease mechanisms, making it an essential marker in immunology and oncology research. Clone RM418, developed using rabbit monoclonal technology, offers superior affinity and specificity compared to traditional mouse antibodies, ensuring clear and consistent staining in immunohistochemistry (IHC) on formalin-fixed paraffin-embedded (FFPE) tissues and cancer research applications. This antibody provides crisp membranous and cytoplasmic staining with minimal background, enabling accurate identification of CD25-positive cell populations in lymphoid tissues, tumor biopsies, and peripheral blood samples. The CD25 Rabbit Monoclonal Antibody Clone RM418 is a valuable tool for researchers and clinicians studying T-cell mediated immunity, lymphoma diagnostics, and immune checkpoint regulation, supporting both basic research and clinical applications
RM418
RM418 reacts to Interleukin-2 receptor subunit alpha (CD25)
A peptide corresponding to the N-terminus of human CD25
Immunohistochemistry (IHC)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.