The CD3 Antibody (Rabbit Monoclonal, Clone MRQ-39) is a high-affinity, well-validated antibody specifically designed to detect CD3, a critical component of the T-cell receptor (TCR) complex. CD3 is expressed on the surface of mature T lymphocytes and plays a central role in T-cell activation, antigen recognition, and immune signaling. As a pan–T-cell marker, CD3 is widely used in both research and diagnostic pathology to identify and characterize T-cell populations in normal and diseased tissues. Clone MRQ-39, developed using advanced rabbit monoclonal technology, provides superior sensitivity and specificity over traditional mouse monoclonals. It is optimized for multiple applications, including immunohistochemistry (IHC) on formalin-fixed paraffin-embedded (FFPE) tissues, flow cytometry, and immunofluorescence (IF). In IHC, MRQ-39 offers sharp, membranous staining of T cells, making it especially useful for evaluating lymphoid architecture, tumor-infiltrating lymphocytes (TILs), and distinguishing T-cell lymphomas from other hematopoietic neoplasms. The CD3 Rabbit Monoclonal Antibody Clone MRQ-39 is an essential tool for immunologists, pathologists, and oncology researchers. Its robust performance across a wide range of tissue types makes it invaluable for studies involving immune profiling, autoimmune diseases, immuno-oncology, and transplant monitoring. Whether for routine diagnostics or advanced research, this antibody delivers precise, reproducible results.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Tonsil
Membrane
IgG
A recombinant human CD3e protein fragment (around aa 23-119)