CD31 / PECAM-1 (Endothelial Cell Marker) is a transmembrane glycoprotein highly expressed on endothelial cells and plays a critical role in cell adhesion, migration, and angiogenesis. Clone PECA1/848 is a concentrated monoclonal antibody specifically designed for the sensitive and specific detection of CD31 in tissue samples. It is widely used as a reliable marker for identifying endothelial cells in both normal and pathological conditions, including studies of vascular tumors and angiogenesis.
Mouse
Recombinant human PECAM1 protein
PECA1/848
IgG1, kappa
Human. Others not known.
Tonsil, Angiosarcoma.
Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare.
Cell surface and cytoplasmic