The CD34 Antibody (Rabbit Monoclonal, Clone EP88) is a premium-quality, high-affinity antibody specifically engineered for the reliable detection of CD34, a type I transmembrane glycoprotein and well-established marker of hematopoietic stem and progenitor cells, as well as vascular endothelial cells. CD34 is crucial in identifying early-stage blood cells and evaluating vascular integrity, and it is widely utilized in research and diagnostics involving stem cell biology, angiogenesis, and vascular tumors. Clone EP88 is developed using proprietary rabbit monoclonal antibody technology to deliver superior sensitivity, specificity, and low background staining, particularly in formalin-fixed paraffin-embedded (FFPE) tissues. This clone produces strong, crisp membranous staining of CD34-positive cells in bone marrow, peripheral blood, spleen, and a wide range of tumor tissues, making it exceptionally suited for immunohistochemistry (IHC) and tissue-based diagnostics. Its robust performance also extends to flow cytometry and immunofluorescence (IF) in research settings. In pathology, the CD34 Rabbit Monoclonal Antibody Clone EP88 is an indispensable tool for identifying and quantifying microvessel density (MVD) in tumor tissues, which is essential for angiogenesis studies, prognostic evaluations, and anti-angiogenic drug development. It is also widely used to differentiate vascular tumors (such as hemangiomas, angiosarcomas, and Kaposi sarcoma) from other neoplasms. In addition, CD34 staining aids in the diagnosis and grading of soft tissue tumors, including solitary fibrous tumors, gastrointestinal stromal tumors (GISTs), and dermatofibrosarcoma protuberans. This antibody is also highly valuable in stem cell research, allowing for the detection and isolation of CD34-positive hematopoietic stem and progenitor cells in bone marrow and peripheral blood, which is critical for bone marrow transplantation, gene therapy, and regenerative medicine applications.
EP88
EP88 reacts to human, mouse and rat CD34.
A peptide corresponding to the C-terminus of human CD34
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
