CD35 / CR1 (Follicular Dendritic Cell Marker)

Clone E11 (Concentrate)

The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-.

Specifications

Species

Mouse

Immunogen

Intact human monocytes

Clone

E11

Isotype

IgG1, kappa

Species Reactivity

Human, Baboon, Cynomolgus Monkey, Rhesus Monkey.

Positive Control

Follicular dendritic cells (FDC) in tonsil.

Specificity

Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35.

Status

RUO