CD44 / HCAM is a widely expressed cell surface glycoprotein that mediates cell adhesion, migration, and signaling, playing a significant role in immune responses and tumor progression. Clone HCAM/918 is a concentrated monoclonal antibody designed for the specific detection of standard CD44 isoforms in formalin-fixed, paraffin-embedded tissues. It is commonly used in research and diagnostic applications to evaluate a range of cancers, including lymphomas and carcinomas, as well as in studies of cell proliferation and metastasis.
Mouse
Recombinant human HCAM protein
HCAM/918
IgG2a, kappa
Human and non-human Primates. Others not tested.
HeLa cells or paracortex in tonsil or lymph node.
Recognizes a cell surface glycoprotein of 80-95kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leukocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin.
Cell surface