The CD44 (MRQ-13) Mouse Monoclonal Antibody is a highly specific and sensitive reagent designed for the detection of CD44, a transmembrane glycoprotein involved in cell adhesion, migration, and signaling. CD44 plays a critical role in a variety of biological processes including lymphocyte activation, homing, and tumor metastasis. It is widely recognized as a key marker for cancer stem cells and has been implicated in tumor progression, invasion, and resistance to therapy. Clone MRQ-13 is a mouse-derived monoclonal antibody developed to provide robust and reproducible staining with high specificity for human CD44. This antibody is extensively validated for use in immunohistochemistry (IHC), Western blotting (WB), and flow cytometry (FC), enabling detailed analysis of CD44 expression in formalin-fixed paraffin-embedded (FFPE) tissues, fresh or frozen samples, and cultured cells. In IHC applications, CD44 (MRQ-13) produces distinct membrane and cytoplasmic staining patterns, allowing accurate identification of CD44-positive cell populations in various normal and diseased tissues. This makes it an invaluable tool for cancer research, stem cell biology, and immune profiling. The antibody is affinity-purified and formulated for optimal stability and minimal background, supporting consistent results across multiple experiments.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Colon carcinoma
Cell membrane
IgG
Recombinant Human CD44 protein
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
