CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have a signaling role to increase adhesion. It is expressed on thymocytes and T-lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This monoclonal antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Mouse
Recombinant human ICAM3 protein
ICAM3/1019
IgG2b, kappa
Human. Others not known
HL-60 or THP-1 cells. Lymph node and tonsil
This antibody recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3
Cell surface