The CD56 antibody [123C3.D5] is a mouse monoclonal antibody that specifically targets the CD56 antigen, also known as neural cell adhesion molecule (NCAM). CD56 is a transmembrane glycoprotein primarily expressed on natural killer (NK) cells, a subset of T cells, and neuronal cells. The [123C3.D5] clone is widely used in immunophenotyping applications, particularly in flow cytometry, to identify and isolate NK cells from peripheral blood, bone marrow, and tissues. This antibody is also utilized in immunohistochemistry to detect CD56 expression in tissue samples, making it valuable for diagnosing NK cell lymphomas, neuroendocrine tumors, and small cell cancers. Its ability to distinguish NK cells and neural cells provides important insights into immune function, tumor biology, and immune responses, particularly in cancer and viral infections.
Mouse
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Human
Autophagy, Cardiovascular, Immunology, Neuroscience, Signal Transduction
IgG1 / Kappa
Cell membrane, Secreted
Human Brain, Cerebellum, Neuroblastoma., Pancreas, PBMCs
Membrane preparation of a small cell lung carcinoma