The CD56 (NCAM1) Rabbit Monoclonal Antibody is a highly specific, high-affinity antibody developed for the sensitive detection of CD56, also known as Neural Cell Adhesion Molecule 1 (NCAM1). CD56 is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily and is involved in cell-cell adhesion, synaptic plasticity, neuronal development, and immune surveillance. It is expressed on a variety of normal and neoplastic cells, including natural killer (NK) cells, subsets of activated T cells, neuronal tissues, and neuroendocrine-derived tumors. This rabbit monoclonal antibody provides superior sensitivity and signal clarity for immunohistochemistry (IHC) on formalin-fixed paraffin-embedded (FFPE) tissues, along with excellent performance in flow cytometry, immunofluorescence (IF), and western blotting (WB). It delivers crisp membranous and cytoplasmic staining in CD56-positive tissues, making it ideal for diagnostic and research applications where clear visualization and reproducibility are essential. CD56 is widely recognized as a diagnostic marker in hematopathology, especially for the identification of NK/T-cell lymphomas, plasmacytomas, myelomas, and acute leukemias with NK phenotype. It is also routinely used in identifying neuroendocrine tumors, such as small cell lung carcinoma, Merkel cell carcinoma, and pheochromocytomas. Furthermore, CD56 is a key biomarker in research related to neural cell migration, neurogenesis, multiple sclerosis, and tumor immune evasion.
RM315
RM315 reacts to human CD56 (NCAM1). It may also react to mouse CD56, as predicted by immunogen homology.
A peptide corresponding to the C-terminus of human CD56.
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
