CD61 (2F2) Mouse Monoclonal Antibody

CD61 (2F2) Mouse Monoclonal Antibody

The CD61 (2F2) Mouse Monoclonal Antibody is a highly specific antibody designed to detect CD61, also known as integrin β3, a critical glycoprotein involved in platelet aggregation, cell adhesion, and signal transduction. CD61 is expressed on platelets, megakaryocytes, endothelial cells, and various hematopoietic and tumor cells, making it a vital marker in hematology, thrombosis, and cancer research. Clone 2F2 delivers robust and reproducible staining with excellent specificity and low background, ideal for immunohistochemistry (IHC), flow cytometry (FC), and Western blot (WB) applications. It is validated for use on formalin-fixed, paraffin-embedded (FFPE) tissues, frozen sections, and cultured cells, providing reliable detection of CD61 in a wide range of human tissues and cell types. In IHC, CD61 (2F2) produces strong membrane and cytoplasmic staining patterns, facilitating the identification of platelet and endothelial cell populations, as well as tumor cells expressing integrin β3. This antibody supports research into platelet function, angiogenesis, cancer metastasis, and vascular biology. Produced using hybridoma technology and affinity-purified, the CD61 (2F2) antibody ensures consistent lot-to-lot performance and long-term stability, making it a dependable reagent for both research and diagnostic laboratories. Key Features: Clone: 2F2 Host / Isotype: Mouse / IgG1 Target: CD61 (Integrin β3) Reactivity: Human Applications: Immunohistochemistry (IHC), Flow Cytometry (FC), Western Blot (WB) Sample Types: FFPE tissues, frozen sections, cultured cells Purification: Affinity-purified Storage: Store at −20°C; avoid repeated freeze-thaw cycles Research Applications: Platelet biology and aggregation studies Hematopoiesis and megakaryocyte research Angiogenesis and vascular biology Cancer progression and metastasis analysis Diagnostic pathology for hematological and vascular diseases